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Clin Infect Dis. 2012 Jul;55(2):e5-8. doi: 10.1093/cid/cis412. Epub 2012 Apr 20.

Association between circulating DNA, serum (1->3)-β-D-glucan, and pulmonary fungal burden in Pneumocystis pneumonia.

Author information

1
Laboratoire de Parasitologie-Mycologie, Hôpital Henri Mondor (AP-HP), Créteil, France.

Abstract

Circulating Pneumocystis jirovecii DNA and (1→3)-β-d-glucan determined in 70 serum samples from immunocompromised patients were compared to fungal load in bronchoalveolar lavage fluids assessed using quantitative polymerase chain reaction. Both serum biomarkers are influenced by pulmonary fungal load, which should be taken into account when diagnosing Pneumocystis infection.

PMID:
22523258
DOI:
10.1093/cid/cis412
[Indexed for MEDLINE]

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