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Am Ind Hyg Assoc J. 1990 Oct;51(10):534-40.

Assessment of potential biases in the application of MSHA respirable coal mine dust data to an epidemiologic study.

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Department of Environmental and Industrial Health, University of Michigan, School of Public Health, Ann Arbor 48109-2029.


Systematic errors in exposure data will result in biased estimates of the exposure-response relationship derived from epidemiologic analyses. Thus, adjustment of exposure data to account for identified errors may provide for a more accurate assessment of effect. In preparing to apply respirable coal mine dust exposure data collected by the Mine Safety and Health Administration (MSHA) to a study of the pulmonary status of underground coal miners, an assessment of potential systematic errors was undertaken. Potential errors stemming from adjustment of controls during sampling, concentration-dependent sampling, truncation of sampling results, identified sampling equipment problems, and a disproportionate number of low concentration samples in mine operator-collected samples were identified and evaluated. Methods to account for these errors and adjust mean exposures by mine, occupation, and year are given.

[Indexed for MEDLINE]

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