Format

Send to

Choose Destination
Dev Cell. 2012 Apr 17;22(4):691-2. doi: 10.1016/j.devcel.2012.04.001.

Membrane fission: curvature-sensitive proteins cut it both ways.

Author information

1
CNRS UMR 5207, Laboratoire Charles Coulomb, Université Montpellier II, F-34095 Montpellier Cedex 05, France.

Abstract

Boucrot et al. (2012) demonstrate a membrane fission mechanism independent of nucleotide hydrolysis that is based on membrane insertion of amphipathic helices. They show that, for N-BAR domain proteins, which promote membrane curvature but also contain amphipathic helices, fission is opposed by the BAR domain that stabilizes tubular membrane structures.

PMID:
22516194
DOI:
10.1016/j.devcel.2012.04.001
Free full text

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center