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Emerg Infect Dis. 2012 May;18(5):783-91. doi: 10.3201/eid1805.111366.

Bartonella spp. bacteremia and rheumatic symptoms in patients from Lyme disease-endemic region.

Author information

1
North Carolina State University, Raleigh, North Carolina, USA.

Abstract

Bartonella spp. infection has been reported in association with an expanding spectrum of symptoms and lesions. Among 296 patients examined by a rheumatologist, prevalence of antibodies against Bartonella henselae, B. koehlerae, or B. vinsonii subsp. berkhoffii (185 [62%]) and Bartonella spp. bacteremia (122 [41.1%]) was high. Conditions diagnosed before referral included Lyme disease (46.6%), arthralgia/arthritis (20.6%), chronic fatigue (19.6%), and fibromyalgia (6.1%). B. henselae bacteremia was significantly associated with prior referral to a neurologist, most often for blurred vision, subcortical neurologic deficits, or numbness in the extremities, whereas B. koehlerae bacteremia was associated with examination by an infectious disease physician. This cross-sectional study cannot establish a causal link between Bartonella spp. infection and the high frequency of neurologic symptoms, myalgia, joint pain, or progressive arthropathy in this population; however, the contribution of Bartonella spp. infection, if any, to these symptoms should be systematically investigated.

PMID:
22516098
PMCID:
PMC3358077
DOI:
10.3201/eid1805.111366
[Indexed for MEDLINE]
Free PMC Article

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