Format

Send to

Choose Destination
See comment in PubMed Commons below
Nat Rev Genet. 2012 Apr 18;13(5):329-42. doi: 10.1038/nrg3174.

A beginner's guide to eukaryotic genome annotation.

Author information

1
Department of Human Genetics, Eccles Institute of Human Genetics, School of Medicine, University of Utah, Salt Lake City, Utah 84112-5330, USA. myandell@genetics.utah.edu

Abstract

The falling cost of genome sequencing is having a marked impact on the research community with respect to which genomes are sequenced and how and where they are annotated. Genome annotation projects have generally become small-scale affairs that are often carried out by an individual laboratory. Although annotating a eukaryotic genome assembly is now within the reach of non-experts, it remains a challenging task. Here we provide an overview of the genome annotation process and the available tools and describe some best-practice approaches.

PMID:
22510764
DOI:
10.1038/nrg3174
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Nature Publishing Group
    Loading ...
    Support Center