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Hepat Mon. 2012 Feb;12(2):112-7. doi: 10.5812/hepatmon.822. Epub 2012 Feb 29.

Distribution and risk factors of hepatitis B virus infection in the general population of Central Iran.

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Department of Gastroenterology, Faculty of Medicine, Qom University of Medical Sciences, Qom, IR Iran.



Hepatitis B is the most common chronic viral infection in humans and the most common cause of death among viral hepatitis. As 70% to 80% of chronic hepatitis cases are caused by HBV in Iran, this virus alone is considered the most important cause of liver diseases and the major cause of mortality arising from viral hepatitis cases in Iran.


We planned this study to determine the prevalence of hepatitis B in the general population of Qom, central Iran.


The present study is a cross-sectional study. A total of 3690 samples were collected from 7 rural clusters and 116 urban clusters. Ten teams, each consisting of 2 trained members, were assigned to conduct the sampling and fill the questionnaires. The data were analyzed using SPSS.


The prevalence rate of hepatitis B infection in Qom Province was 1.3%. The mean age of the patients with hepatitis B was 44.17 years. The prevalence of hepatitis B was 1.6% in men and 1.1% in women. Moreover, the prevalence of hepatitis B correlated positively with age, tattooing, and literacy level.


The prevalence rate of hepatitis B in Qom is 1.3%. It is possible to prevent the disease by increasing public awareness. Further investigation on clinical presentations and a determination of the genotype of the virus are suggested.


Hepatitis B; Iran; Prevalence

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