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Chin J Cancer. 2012 Dec;31(12):564-72. doi: 10.5732/cjc.011.10444. Epub 2012 Apr 13.

A new prospect in cancer therapy: targeting cancer stem cells to eradicate cancer.

Author information

1
Nanobiomedicine Division, Suzhou Institute of Nano-Tech and Nano-Bionics, Chinese Academy of Sciences, Suzhou, Jiangsu 215123, P. R. China.

Abstract

According to the cancer stem cell theory, cancers can be initiated by cancer stem cells. This makes cancer stem cells prime targets for therapeutic intervention. Eradicating cancer stem cells by efficient targeting agents may have the potential to cure cancer. In this review, we summarize recent breakthroughs that have improved our understanding of cancer stem cells, and we discuss the therapeutic strategy of targeting cancer stem cells, a promising future direction for cancer stem cell research.

PMID:
22507219
PMCID:
PMC3777459
DOI:
10.5732/cjc.011.10444
[Indexed for MEDLINE]
Free PMC Article

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