Format

Send to

Choose Destination
Physiology (Bethesda). 2012 Apr;27(2):85-99. doi: 10.1152/physiol.00043.2011.

Mechanisms of protein delivery to melanosomes in pigment cells.

Author information

1
Cell and Molecular Biology Graduate Group, Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

Abstract

Vertebrate pigment cells in the eye and skin are useful models for cell types that use specialized endosomal trafficking pathways to partition cargo proteins to unique lysosome-related organelles such as melanosomes. This review describes current models of protein trafficking required for melanosome biogenesis in mammalian melanocytes.

PMID:
22505665
PMCID:
PMC3345138
DOI:
10.1152/physiol.00043.2011
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Atypon Icon for PubMed Central
Loading ...
Support Center