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J Neurosci Methods. 2012 May 30;207(1):86-90. doi: 10.1016/j.jneumeth.2012.03.014. Epub 2012 Apr 5.

Individualized recording chambers for non-human primate neurophysiology.

Author information

1
School of Biological and Health Systems Engineering, and Arizona State University, Tempe, AZ 85287-9709, USA.

Abstract

While neural recording chambers for non-human primates can be purchased commercially, these generic chambers do not contour to the animal's skull. In order to seal gaps, a cap of dental acrylic (methyl methacrylate) is often applied around the chamber. There are multiple disadvantages associated with this method. Applying acrylic delays and further complicates surgical procedure, and overheating during the curing process can cause damage to the bone. Post-surgery, acrylic margins can give rise to bacterial growth and infection. Here we describe a method to develop custom implants which conform to the individual's skull, thereby eliminating the need for acrylic. This method shortens surgery time and significantly improves the hygiene of chamber margins.

PMID:
22498201
PMCID:
PMC3348412
DOI:
10.1016/j.jneumeth.2012.03.014
[Indexed for MEDLINE]
Free PMC Article

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