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Curr Biol. 2012 Apr 10;22(7):R221-3. doi: 10.1016/j.cub.2012.02.056.

Axon degeneration: where the Wlds things are.

Author information

1
Department of Neurobiology, Stanford University School of Medicine, Stanford, CA 94305, USA. jtw@stanford.edu

Abstract

Expression of the Wld(s) protein significantly delays axon degeneration in injuries and diseases, but the mechanism for this protection is unknown. Two recent reports present evidence that axonal mitochondria are required for Wld(S)-mediated axon protection.

PMID:
22497934
PMCID:
PMC4449840
DOI:
10.1016/j.cub.2012.02.056
[Indexed for MEDLINE]
Free PMC Article

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