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Acta Otolaryngol. 2012 Jun;132(6):632-6. doi: 10.3109/00016489.2011.653443. Epub 2012 Apr 12.

Furosemide-loading vestibular evoked myogenic potential testing can suggest developing bilateral involvement of unilateral Meniere's disease.

Author information

1
Department of Otolaryngology, Osaka Central Hospital, Osaka, Japan. tseo@osaka-centralhp.jp

Abstract

CONCLUSIONS:

Patients with positive results of furosemide-loading vestibular evoked myogenic potential (F-VEMP) testing in the unaffected ears of unilateral Meniere's disease have a high incidence of developing bilateral lesions.

OBJECTIVE:

To clarify the meaning of positive results of F-VEMP testing of the unaffected ear of patients with unilateral Meniere's disease.

METHODS:

Twenty-five patients with unilateral Meniere's disease were investigated in this study. The positive group consisted of 6 patients with positive results of F-VEMP testing in the contralateral ear and the negative group consisted of 19 patients with negative results. The incidence of contralateral involvement was compared in both groups by the Kaplan-Meier method.

RESULTS:

Contralateral involvement was seen in three cases (50%) in the positive group after 2, 12, and 26 months and in three cases (16%) in the negative group after 27, 56, and 78 months. The positive group had a higher incidence of contralateral involvement than the negative group (p = 0.0017, according to a log-rank test).

PMID:
22497197
DOI:
10.3109/00016489.2011.653443
[Indexed for MEDLINE]

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