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Knee Surg Sports Traumatol Arthrosc. 2013 Apr;21(4):824-9. doi: 10.1007/s00167-012-1980-z. Epub 2012 Apr 10.

Platelet-rich plasma: does it help reduce tunnel widening after ACL reconstruction?

Author information

1
Orthopaedic Unit and Kirk Kilgour Sports Injury Centre, S. Andrea Hospital, University of Rome La Sapienza, Via Grottarossa, 1035, Rome, Italy. anto.vada@libero.it

Abstract

PURPOSE:

The purpose of this study was to evaluate the efficacy of platelet-rich plasma (PRP) in reducing femoral and tibial tunnel enlargement in patients operated on for anterior cruciate ligament reconstruction with hamstrings.

METHODS:

Forty male patients, in which both femoral and tibial 9-mm tunnels were performed because of the graft size, were enrolled in this prospective study. They were randomly assigned to group A (20 patients, PRP group) and group B (20 patients, control group). All patients were followed up at a median of 14.7 months (range 10-16 months), with a physical examination, the Tegner, Lysholm and objective IKDC scoring scales, and with the KT-1000 arthrometer. Moreover, they underwent a CT evaluation in order to assess the amount of tunnel enlargement.

RESULTS:

Femoral tunnel diameter increased from 9.0 ± 0.1 mm to 9.8 ± 0.3 mm in group A (p = 0.032) and from 9.0 ± 0.1 mm to 9.4 ± 0.5 mm in group B (p = 0.043). Tibial tunnel diameter increased from 9.0 ± 0.2 mm to 10.9 ± 0.2 mm in group A (p = 0.029) and from 9.1 ± 0.1 mm to 10.1 ± 0.4 mm in group B (p = 0.028). Physical examination as well as the evaluation scales used showed no differences between the two groups.

CONCLUSIONS:

The use of PRP does not seem to be effective in preventing tunnel enlargement.

PMID:
22488012
DOI:
10.1007/s00167-012-1980-z
[Indexed for MEDLINE]

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