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Curr Alzheimer Res. 2012 Jul;9(6):646-63.

Overview and findings from the rush Memory and Aging Project.

Author information

1
Rush Alzheimer's Disease Center, Rush University Medical Center, 600 S. Paulina, Suite 1028, Chicago, IL 60612, USA. David_A_Bennett@Rush.edu

Abstract

The Memory and Aging Project is a longitudinal, epidemiologic clinical-pathologic cohort study of common chronic conditions of aging with an emphasis on decline in cognitive and motor function and risk of Alzheimer's disease (AD). In this manuscript, we first summarize the study design and methods. Then, we present data on: (1) the relation of motor function to cognition, disability, and death; (2) the relation of risk factors to cognitive and motor outcomes, disability and death; (3) the relation of neuropathologic indices to cognitive outcomes; (4) the relation of risk factors to neuropathologic indices; and (5) additional study findings. The findings are discussed and contextualized.

PMID:
22471867
PMCID:
PMC3439198
[Indexed for MEDLINE]
Free PMC Article

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