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Indian J Endocrinol Metab. 2012 Mar;16(2):164-76. doi: 10.4103/2230-8210.93732.

Rickets-vitamin D deficiency and dependency.

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1
Department of Nephrology, Osmania Medical College and General Hospital, Hyderabad, Andhra Pradesh, India.

Abstract

Rickets is an important problem even in countries with adequate sun exposure. The causes of rickets/osteomalacia are varied and include nutritional deficiency, especially poor dietary intake of vitamin D and calcium. Non-nutritional causes include hypophosphatemic rickets primarily due to renal phosphate losses and rickets due to renal tubular acidosis. In addition, some varieties are due to inherited defects in vitamin D metabolism and are called vitamin D dependent rickets. This chapter highlights rickets/osteomalacia related to vitamin D deficiency or to inherited defects in vitamin D metabolism. Hypophosphatemic rickets and rickets due to renal tubular acidosis are discussed in other sections of the journal.

KEYWORDS:

Osteomalacia; Vitamin D; Vitamin D deficiency; Vitamin D dependent rickets; rickets

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