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Hepatogastroenterology. 2012 May;59(115):930-3. doi: 10.5754/hge09356.

Prognostic predictors of patients with carcinoma of the gastric cardia.

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1
Department of Breast Surgery, Harbin Medical University, Harbin, China.

Abstract

BACKGROUND/AIMS:

This study gives insight into survival predictors and clinicopathological features of carcinoma of the gastric cardia.

METHODOLOGY:

The study included 233 patients who underwent operation for carcinoma of the gastric cardia. Clinicopathological prognostic variables were evaluated as predictors of long-term survival by univariate and multivariate analysis. Cox regression was used for multivariate analysis and survival curves were drawn by the Kaplan- Meier method.

RESULTS:

Carcinoma of the gastric cardia was characterized by positive lymph node metastasis (77.3%), serosal invasion (83.3%) and more stage III or IV tumors (72.5%). Overall 5-year survival rate was 21.9% and median survival period was 24 months. The 5-year survival rate was influenced by tumor size, depth on invasion, lymph node metastasis, extent of lymph node dissection, disease stage, operation methods and resection margin.

CONCLUSIONS:

The absent of serosal invasion and lymph node metastasis, curative resection should be considered to be the favourable predictors of long-term survival of patients with carcinoma of the gastric cardia.

PMID:
22469742
DOI:
10.5754/hge09356
[Indexed for MEDLINE]

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