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Mayo Clin Proc. 2012 Apr;87(4):403-7. doi: 10.1016/j.mayocp.2011.11.016.

Nocardiosis: updates and clinical overview.

Author information

1
Division of Infectious Diseases, Mayo Clinic, Rochester, MN 55905, USA. wilson.john@mayo.edu

Abstract

Nocardia, a gram-positive bacillus with the microscopic appearance of branching hyphae, can produce considerable disease in the appropriate host. The taxonomy of Nocardia continues to evolve; more than 50 species have been described. Early recognition and effective therapy are imperative to achieve successful outcomes. Although nocardiosis typically occurs in patients with cell-mediated immunosuppressive conditions, infection may occasionally develop in immunocompetent patients as well. This review addresses the microbiology of Nocardia, risk factors for infection, clinical presentations, and management strategies.

PMID:
22469352
PMCID:
PMC3498414
DOI:
10.1016/j.mayocp.2011.11.016
[Indexed for MEDLINE]
Free PMC Article

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