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Indian J Clin Biochem. 2011 Apr;26(2):210-3. doi: 10.1007/s12291-010-0100-4. Epub 2011 Jan 19.

Comparison Between Serum hsCRP and LDL Cholesterol for Search of a Better Predictor for Ischemic Heart Disease.

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Department of Biochemistry, Katihar Medical College, Katihar, Bihar India.


Acute myocardial Infarction is one of the major causes of morbidity & mortality in world and atherosclerosis is the major cause of ischemic heart disease. In order to determine the better clinical marker of atherosclerosis, we estimated serum low-density lipoprotein (LDL-C) and high sensitivity C-reactive protein (hsCRP). Hundred patients of myocardial infarction and 100 controls irrespective of age and sex were studied for these parameters over a period of 2 years. The statistical analysis showed that the serum hsCRP was significantly raised in myocardial infarction cases than controls (P < 0.01) but LDL-C was not (P > 0.05). We conclude that the serum hsCRP has better predictive value for risk of atherosclerosis.


Atherosclerosis; LDL cholesterol; Myocardial infarction; hsCRP

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