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J Clin Ultrasound. 2012 Nov-Dec;40(9):594-7. doi: 10.1002/jcu.21915. Epub 2012 Mar 29.

Sirenomelia apus after trimethoprim exposure: first-trimester ultrasound diagnosis-a case report.

Author information

1
Slovak Medical University, Bratislava, III. Department of Gynaecology and Obstetrics, 1st Private Hospital Košice-Šaca Inc., Košice-Šaca, Slovak Republic.

Abstract

We report the early prenatal ultrasound diagnosis of sirenomelia apus at 12+4 weeks in a patient with trimethoprim exposure in the vulnerable period. First-trimester scan revealed a malformed fetus with one femur, one small tibia, no feet, intraabdominal unilocular cystic structure, and two-vessel umbilical cord with allantoic cyst. Ultrasound visualization with two/three/four-dimensions was helpful in the process of parental counseling.

PMID:
22467597
DOI:
10.1002/jcu.21915
[Indexed for MEDLINE]

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