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Retina. 2012 Sep;32(8):1601-7. doi: 10.1097/IAE.0b013e3182437e70.

Sector laser photocoagulation for the prevention of macular edema after plaque radiotherapy for uveal melanoma: a pilot study.

Author information

1
Ocular Oncology Service, Wills Eye Institute, Thomas Jefferson University, Philadelphia, Pennsylvania, USA. miguel.materin@yale.edu

Abstract

OBJECTIVE:

To investigate the role of sector laser photocoagulation for prevention of macular edema after plaque radiotherapy for uveal melanoma.

METHODS:

Noncomparative, pilot interventional case series. The main outcome measure was optical coherence tomography-evident macular edema.

RESULTS:

A total of 29 patients had sector laser photocoagulation (sector panretinal photocoagulation) and sub-Tenon triamcinolone injection. The median tumor thickness and base was 3.3 mm and 10.0 mm. The median radiation dose and rate to the macula was 2,944 cGy and 31.0 cGy/hour. At the 12-month and 24-months follow-up, cystoid macular edema was found in 17% and 24% of the sector panretinal photocoagulation group. There were no major side effects registered.

CONCLUSION:

Sector panretinal photocoagulation in combination with sub-Tenon triamcinolone appears to show potential as a safe and beneficial intervention for the prevention of macular edema after plaque radiotherapy for uveal melanoma in this series.

PMID:
22466484
DOI:
10.1097/IAE.0b013e3182437e70
[Indexed for MEDLINE]
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