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Fitoterapia. 2012 Jun;83(4):801-5. doi: 10.1016/j.fitote.2012.03.016. Epub 2012 Mar 20.

Four new sesquiterpenes from Commiphora myrrha and their neuroprotective effects.

Author information

1
College of Pharmacy, State Key Laboratory of Medicinal Chemical Biology and Tianjin Key Laboratory of Molecular Drug Research, Nankai University, Tianjin 300071, China.

Abstract

Four new sesquiterpenes, myrrhterpenoids K-N (1-4) have been isolated from the resin of Commiphora myrrha. Their structures and relative configurations were elucidated by spectroscopic methods (IR, ESIMS, HR-ESIMS, 1D and 2D NMR). Compounds 1 and 4 showed neuroprotective effects against MPP(+)-induced neuronal cell death in SH-SY5Y cells.

PMID:
22465505
DOI:
10.1016/j.fitote.2012.03.016
[Indexed for MEDLINE]

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