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Int J Stroke. 2012 Jul;7(5):435-9. doi: 10.1111/j.1747-4949.2012.00784.x. Epub 2012 Mar 30.

Blood biomarkers in stroke: research and clinical practice.

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Division of Clinical Neurosciences, Western General Hospital, University of Edinburgh, Edinburgh, UK.


Blood biomarkers may have applications in stroke diagnosis, outcome prediction, or treatment. In this article, we provide a focused review on some of the methodological challenges and potential developments of biomarkers in stroke. We review the approaches to the development of a diagnostic blood marker: a candidate marker approach, marker panels, and -omics. Then we examined the role of blood markers to predict recurrent stroke and treatment response in stroke.

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