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J Bacteriol. 2012 Apr;194(8):2107-8. doi: 10.1128/JB.06631-11.

Genome sequence of Staphylococcus aureus VC40, a vancomycin- and daptomycin-resistant strain, to study the genetics of development of resistance to currently applied last-resort antibiotics.

Author information

  • 1Institute of Medical Microbiology, Immunology and Parasitology (IMMIP), University of Bonn, Bonn, Germany. psass@uni-bonn.de

Abstract

The increasing emergence of multidrug-resistant Staphylococcus aureus is a problem of global importance. Here, we report the genome of S. aureus VC40, which is resistant to the last-resort antibiotics vancomycin and daptomycin. Its genome sequence will allow insights into the mechanisms that convey full resistance to these compounds.

PMID:
22461548
PMCID:
PMC3318483
DOI:
10.1128/JB.06631-11
[PubMed - indexed for MEDLINE]
Free PMC Article
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