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Clin Lab Sci. 2012 Winter;25(1):45-9.

Anti-hormones: mechanism and use in treatment of breast cancer.

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  • 1School of Health Science, Biomedical Diagnostic & Therapeutic Sciences, 356 HH, Oakland University, Rochester, MI 48309, USA.


Breast cancer is the second-leading cause of cancer-related death in women. Recently, new drugs are being developed based on the molecular mechanisms of receptors, tumor suppressor genes, monoclonal antibodies, tumor markers and antihormone therapy. Anti-hormone therapy is used in the treatment of hormone-dependent breast tumors. Among the anti-hormone therapies, a substantial amount of research has been focused on the development of the ideal selective estrogen receptor modulator to treat metastatic breast tumors and to prevent breast cancer in high risk women.

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