Glass nanopillar arrays with nanogap-rich silver nanoislands for highly intense surface enhanced Raman scattering

Adv Mater. 2012 May 2;24(17):2234-7. doi: 10.1002/adma.201104696. Epub 2012 Mar 27.

Abstract

The enhancement of surface enhanced Raman scattering (SERS) with nanogap-rich silver nanoislands surrounding glass nanopillars at wafer level is reported. High-density hot spots are generated by increasing the number of nanogap-rich nanoislands within a detection volume. The SERS substrate shows a high enhancement factor of over 10(7) with excellent signal uniformity (∼7.8%) and it enables the label-free detection of aqueous DNA base molecules at nanomolar level.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • DNA / chemistry
  • Glass
  • Nanostructures / chemistry*
  • Nanostructures / ultrastructure
  • Nanotechnology
  • Silver / chemistry*
  • Spectrum Analysis, Raman*

Substances

  • Silver
  • DNA