Anxiolytic activity of tenoten and diazepam depends on conditions in Vogel conflict test

I A Kheyfets; T A Voronina; J L Dugina; G M Molodavkin; S A Sergeeva

doi:10.1007/s10517-011-1324-x

Anxiolytic activity of tenoten and diazepam depends on conditions in Vogel conflict test

Bull Exp Biol Med. 2011 Jul;151(3):336-9. doi: 10.1007/s10517-011-1324-x.

[Article in English, Russian]

Authors

I A Kheyfets¹, T A Voronina, J L Dugina, G M Molodavkin, S A Sergeeva

Affiliation

¹ Materia Medica Holding, Moscow, Russia. nauka@materiamedica.ru

PMID: 22451881
DOI: 10.1007/s10517-011-1324-x

Abstract

We compared two modifications of Vogel conflict test and assessed anxyolitic activity of two drugs: diazepam (benzodiazepine anxiolitic) and tenoten (ultra-low doses of antibodies to S-100 protein) in both modifications of the test. It was found that the intensity of anxiolitic effect of the drugs depends on the conditions of Vogel test.

Publication types

Comparative Study

MeSH terms

Animals
Anti-Anxiety Agents / pharmacology*
Antibodies / pharmacology*
Anxiety / drug therapy*
Behavior, Animal / drug effects
Diazepam / pharmacology*
Drug Evaluation, Preclinical
Electroshock
Male
Rats
Water Deprivation

Substances

Anti-Anxiety Agents
Antibodies
tenoten
Diazepam