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J Biotechnol. 2012 Nov 30;162(1):50-6. doi: 10.1016/j.jbiotec.2012.03.005. Epub 2012 Mar 16.

Cyanobacterial biofuel production.

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1
Department of Chemistry, University of California, Davis, CA 95616, USA.

Abstract

The development of new technologies for production of alternative fuel became necessary to circumvent finite petroleum resources, associate rising costs, and environmental concerns due to rising fossil fuel CO₂ emissions. Several alternatives have been proposed to develop a sustainable industrial society and reduce greenhouse emissions. The idea of biological conversion of CO₂ to fuel and chemicals is receiving increased attention. In particular, the direct conversion of CO₂ with solar energy to biofuel by photosynthetic microorganisms such as microalgae and cyanobacteria has several advantages compared to traditional biofuel production from plant biomass. Photosynthetic microorganisms have higher growth rates compared with plants, and the production systems can be based on non-arable land. The advancement of synthetic biology and genetic manipulation has permitted engineering of cyanobacteria to produce non-natural chemicals typically not produced by these organisms in nature. This review addresses recent publications that utilize different approaches involving engineering cyanobacteria for production of high value chemicals including biofuels.

PMID:
22446641
DOI:
10.1016/j.jbiotec.2012.03.005
[Indexed for MEDLINE]

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