Format

Send to

Choose Destination
Psychiatry Res. 1990 Aug;33(2):171-7.

Correlates of rapid neuroleptic response in male patients with schizophrenia.

Author information

1
Schizophrenia Biologic Research Center, Department of Veterans Affairs Medical Center, Palo Alto, CA.

Abstract

Correlates of neuroleptic response latency were assessed in 16 male schizophrenic inpatients during 4 weeks of fixed dose (20 mg/day) haloperidol treatment. Rapid responders showed a mean 40% reduction in Brief Psychiatric Rating Scale (BPRS) positive symptom scores by day 10 of treatment. Rapid responders had significantly lower plasma homovanillic acid (pHVA) concentrations compared to non-rapid responders during week 4 of haloperidol treatment. However, rapid versus non-rapid responders did not differ with respect to demographics, baseline positive or negative BPRS symptom scores, performance on tests of neuropsychological function, or mean plasma haloperidol concentrations.

PMID:
2243894
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center