Format

Send to

Choose Destination
See comment in PubMed Commons below
Endocrinology. 2012 Jun;153(6):2551-5. doi: 10.1210/en.2011-2134. Epub 2012 Mar 20.

Understanding the sexome: measuring and reporting sex differences in gene systems.

Author information

1
Department of Integrative Biology and Physiology, University of California, Los Angeles, California 90095-7239, USA. arnold@ucla.edu

Abstract

The current male bias in biomedical research should be eliminated. The large sex differences in incidence and progression of diseases mean that sex-biased factors are an untapped source of factors that protect from disease. Greater understanding will come from intensified study of the "sexome," which is the sum of sex-biased effects on gene networks and cell systems. The global search for sites and mechanisms of sex-specific regulation in diverse tissues will provide unanticipated insights into physiological regulation and targets for novel therapies.

PMID:
22434084
PMCID:
PMC3359607
DOI:
10.1210/en.2011-2134
[Indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Silverchair Information Systems Icon for PubMed Central
    Loading ...
    Support Center