Format

Send to

Choose Destination
See comment in PubMed Commons below
Int Urogynecol J. 2012 Aug;23(8):993-1005. doi: 10.1007/s00192-012-1691-5. Epub 2012 Mar 17.

A systematic review of clinical studies of electrical stimulation for treatment of lower urinary tract dysfunction.

Author information

1
Princess Anne Hospital, Urodynamics Unit, Level G, Coxford Road, Southampton S016 5YA, UK. ashmonga@aol.com

Abstract

INTRODUCTION AND HYPOTHESIS:

The aim of this manuscript was to provide a systematic literature review of clinical trial evidence for a range of electrical stimulation therapies in the treatment of lower urinary tract symptoms (LUTS).

METHODS:

The databases MEDLINE, BIOSIS Previews, Inside Conferences, and EMBASE were searched. Original clinical studies with greater than 15 subjects were included.

RESULTS:

Seventy-three studies were included, representing implanted sacral nerve stimulation (SNS), percutaneous posterior tibial nerve stimulation (PTNS), and transcutaneous electrical stimulation (TENS) therapy modalities.

CONCLUSIONS:

Median mean reductions in incontinence episodes and voiding frequency were similar for implanted SNS and PTNS. However, long-term follow-up data to validate the sustained benefit of PTNS are lacking. Despite a substantial body of research devoted to SNS validation, it is not possible to definitively define the appropriate role of this therapy owing largely to study design flaws that inhibited rigorous intention to treat analyses for the majority of these studies.

PMID:
22426872
DOI:
10.1007/s00192-012-1691-5
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Springer
    Loading ...
    Support Center