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Lab Chip. 2012 May 7;12(9):1594-7. doi: 10.1039/c2lc21266h. Epub 2012 Mar 16.

Mesh-integrated microdroplet array for simultaneous merging and storage of single-cell droplets.

Author information

1
Department of Bio and Brain Engineering, Korea Advanced Institute of Science and Technology (KAIST), Yuseong-gu, Daejeon, Republic of Korea.

Abstract

We constructed a mesh-grid integrated microwell array which enables easy trapping and consistent addition of droplets. The grid acts as a microchannel structure to guide droplets into the microwells underneath, and also provides open access for additional manipulation in a high-throughput manner. Each droplet in the array forms a stable environment of pico-litre volume to implement a single-cell-based assay.

PMID:
22422143
DOI:
10.1039/c2lc21266h
[Indexed for MEDLINE]

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