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J Clin Endocrinol Metab. 2012 May;97(5):1420-2. doi: 10.1210/jc.2011-2845. Epub 2012 Mar 14.

Anemia and thrombocytopenia improves after curative parathyroidectomy in a patient of primary hyperparathyroidism (PHPT).

Author information

1
Department of Endocrinology, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh 160012, India. bhadadask@rediffmail.com

Abstract

CONTEXT:

Hematological manifestations are less known in primary hyperparathyroidism (PHPT). Anemia has been recognized as a complication of PHPT in 5-30% of the individuals in various series.

OBJECTIVE:

Our objective was to identify hematological improvement after the curative parathyroidectomy in a PHPT patient with anemia and thrombocytopenia.

PATIENT AND METHODS:

A 30-yr-old female presented with recurrent renal stone disease, anemia, and thrombocytopenia diagnosed as PHPT. Bone marrow examination revealed megakaryocytic thrombocytopenia. Two months after the curative parathyroidectomy, her symptoms and hematological parameters were improved.

CONCLUSION:

Our finding showed a causal association of both anemia and thrombocytopenia with marrow fibrosis in a symptomatic PHPT patient because both anemia and thrombocytopenia improved after the curative parathyroidectomy.

PMID:
22419706
DOI:
10.1210/jc.2011-2845
[Indexed for MEDLINE]

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