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Biofactors. 2012 Mar-Apr;38(2):114-22. doi: 10.1002/biof.1002. Epub 2012 Mar 15.

Ascorbic acid, cognitive function, and Alzheimer's disease: a current review and future direction.

Author information

1
Department of Neurology, CR-131, Oregon Health and Science University, Portland, OR, USA. bowmang@ohsu.edu

Abstract

This narrative review appraises the human and animal studies implicating ascorbic acid (AA) in normal cognitive function and Alzheimer's disease. A research framework for how nutrition affects brain aging is proposed with emphasis on AA intake, status, metabolism, and transport into brain tissue. A final synopsis highlights areas for future research regarding AA nourishment and healthy brain aging.

PMID:
22419527
PMCID:
PMC3594659
DOI:
10.1002/biof.1002
[Indexed for MEDLINE]
Free PMC Article

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