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Prenat Diagn. 2012 Feb;32(2):122-6. doi: 10.1002/pd.2906.

Fetal reduction of triplet pregnancy: one or two?

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Département d'Echographie et de Médecine Fœtale, Hôpitaux Universitaire de Strasbourg-Centre Médico-Chirurgical et Obstétrical (HUS-CMCO), Schiltigheim, France.



To review outcomes following reductions in trichorionic triplet pregnancies at our institution.


Retrospective analysis of the outcome of trichorionic triamniotic triplets reduced to singletons (group I, n = 44) or twins (group II, n = 136) at 10 and 12 weeks of gestation.


Reduction to one or two was based on parent's preference, hence unrelated to any specific obstetrical or maternal issue. Early fetal loss rate (e.g. <24 weeks) was 9.1% in group I versus 5.1% in group II (p = 0.83). In group I, the take-home baby rate was 86.4% versus 91.9% in group II (p = 0.8). In group I, 17.5% of the women gave birth between 33 and 36(+6) weeks of gestation versus 40.6% in group II (p = 0.026). Delivery beyond 37 weeks was 72.5% in group I and 46.9% in group II (p = 0.01). Intrauterine growth restriction rate was 27.0% in group I versus 45.0% in group II (p = 0.049).


Reduction to one rather than two fetuses led to significantly higher term delivery rate without significant differences in fetal loss rate or take-home baby rate.

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