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Curr HIV/AIDS Rep. 2012 Jun;9(2):160-70. doi: 10.1007/s11904-012-0114-z.

HIV-1 prevention for HIV-1 serodiscordant couples.

Author information

1
International Clinical Research Center, Department of Global Health, University of Washington, Seattle, WA 98104, USA. kgcurran@uw.edu

Abstract

A substantial proportion of HIV-1 infected individuals in sub-Saharan Africa are in stable relationships with HIV-1 uninfected partners, and HIV-1 serodiscordant couples thus represent an important target population for HIV-1 prevention. Couple-based HIV-1 testing and counseling facilitates identification of HIV-1 serodiscordant couples, counseling about risk reduction, and referrals to HIV-1 treatment, reproductive health services, and support services. Maximizing HIV-1 prevention for HIV-1 serodiscordant couples requires a combination of strategies, including counseling about condoms, sexual risk, fertility, contraception, and the clinical and prevention benefits of antiretroviral therapy (ART) for the HIV-1-infected partner; provision of clinical care and ART for the HIV-1-infected partner; antenatal care and services to prevent mother-to-child transmission for HIV-1-infected pregnant women; male circumcision for HIV-1-uninfected men; and, pending guidelines and demonstration projects, oral pre-exposure prophylaxis (PrEP) for HIV-1-uninfected partners.

PMID:
22415473
PMCID:
PMC3570050
DOI:
10.1007/s11904-012-0114-z
[Indexed for MEDLINE]
Free PMC Article

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