Format

Send to

Choose Destination
See comment in PubMed Commons below
Mar Drugs. 2012 Feb;10(2):427-38. doi: 10.3390/md10020427. Epub 2012 Feb 15.

Terpenoids from the octocorals Menella sp. (Plexauridae) and Lobophytum crassum (Alcyonacea).

Author information

1
Department of Biomedical Engineering, National Cheng Kung University, Tainan 701, Taiwan. 298f@vghtc.gov.tw

Abstract

A new germacrane-type sesquiterpenoid, menelloide E (1), and a new cembrane-type diterpenoid, lobocrassin F (2), were isolated from the octocorals Menella sp. and Lobophytum crassum, respectively. The structures of terpenoids 1 and 2 were determined by spectroscopic and chemical methods and compound 2 was found to display a significant inhibitory effect on the release of elastase by human neutrophils.

KEYWORDS:

Lobophytum; Menella; cembrane; elastase ; germacrane; lobocrassin; menelloide

PMID:
22412810
PMCID:
PMC3297006
DOI:
10.3390/md10020427
[Indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments

    Supplemental Content

    Full text links

    Icon for Multidisciplinary Digital Publishing Institute (MDPI) Icon for PubMed Central
    Loading ...
    Support Center