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Mar Drugs. 2012 Feb;10(2):319-28. doi: 10.3390/md10020319. Epub 2012 Feb 3.

Five new amicoumacins isolated from a marine-derived bacterium Bacillus subtilis.

Author information

1
KAUST Global Collaborative Research, Division of Life Science, Hong Kong University of Science and Technology, Clear Water Bay, Hong Kong, China. liyongxin@ust.hk

Abstract

Four novel amicoumacins, namely lipoamicoumacins A-D (1-4), and one new bacilosarcin analog (5) were isolated from culture broth of a marine-derived bacterium Bacillus subtilis, together with six known amicoumacins. Their structures were elucidated on the basis of extensive spectroscopic (2D NNR, IR, CD and MS) analysis and in comparison with data in literature.

KEYWORDS:

Bacillus subtilis; antibacterial; cytotoxicity; lipoamicoumacin

PMID:
22412803
PMCID:
PMC3296999
DOI:
10.3390/md10020319
[Indexed for MEDLINE]
Free PMC Article

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