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Sensors (Basel). 2009;9(6):4407-45. doi: 10.3390/s90604407. Epub 2009 Jun 5.

Antibody-based sensors: principles, problems and potential for detection of pathogens and associated toxins.

Author information

1
Centre for Bioanalytical Sciences (CBAS), Dublin City University, Dublin 9, Ireland; E-Mail: Barry.Byrne@dcu.ie (B.B.).

Abstract

Antibody-based sensors permit the rapid and sensitive analysis of a range of pathogens and associated toxins. A critical assessment of the implementation of such formats is provided, with reference to their principles, problems and potential for 'on-site' analysis. Particular emphasis is placed on the detection of foodborne bacterial pathogens, such as Escherichia coli and Listeria monocytogenes, and additional examples relating to the monitoring of fungal pathogens, viruses, mycotoxins, marine toxins and parasites are also provided.

KEYWORDS:

antibody; assay development; biosensor; electrochemical; pathogen; surface-plasmon resonance

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