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Int J Mol Sci. 2012;13(2):2091-109. doi: 10.3390/ijms13022091. Epub 2012 Feb 16.

Antioxidant-induced stress.

Author information

1
Escuela Superior de Medicina del IPN, Posgrado e Investigacion, Plan de San Luis y Salvador Diaz Miron S/N, Colonia Casco de Santo Tomas, Mexico, DF. 11340, Mexico.

Abstract

Antioxidants are among the most popular health-protecting products, sold worldwide without prescription. Indeed, there are many reports showing the benefits of antioxidants but only a few questioning the possible harmful effects of these "drugs". The normal balance between antioxidants and free radicals in the body is offset when either of these forces prevails. The available evidence on the harmful effects of antioxidants is analyzed in this review. In summary, a hypothesis is presented that "antioxidant-induced stress" results when antioxidants overwhelm the body's free radicals.

KEYWORDS:

antioxidant; harmful effects; oxidative stress

PMID:
22408440
PMCID:
PMC3292009
DOI:
10.3390/ijms13022091
[Indexed for MEDLINE]
Free PMC Article
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