Format

Send to

Choose Destination
See comment in PubMed Commons below
Mol Med Rep. 2012 Jun;5(6):1375-81. doi: 10.3892/mmr.2012.826. Epub 2012 Mar 7.

Diverse functions of uterine proteoglycans in human reproduction (review).

Author information

1
IVF Center, Oak Clinic, Osaka, Japan.

Abstract

Proteoglycans (PGs) are a group of heavily glycosylated proteins that are present throughout the mammalian body and are involved in a wide variety of biological phenomena, including structural maintenance, tissue remodeling, molecular presentation, cell adhesion and signal transmission. Previous studies have revealed an increasing number of roles for PGs in human reproduction. Several PGs are currently utilized or regarded as biomarkers for the diagnosis of certain pathological uterine conditions associated with infertility and obstetrical complications. The aim of this review was to discuss the involvement of PGs in the human uterus in reproductive biology and pathophysiology.

PMID:
22406817
DOI:
10.3892/mmr.2012.826
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Spandidos Publications
    Loading ...
    Support Center