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Cell Metab. 2012 Mar 7;15(3):277-8. doi: 10.1016/j.cmet.2012.02.010.

Irisin, turning up the heat.

Author information

1
Departament de Bioquímica i Biología Molecular and Institut de Biomedicina, Universitat de Barcelona, 08028 Barcelona, Catalonia, Spain. fvillarroya@ub.edu

Abstract

Exercise exerts beneficial effects on systemic metabolism. A recent Nature paper (Boström et al., 2012) identifies irisin as an exercise-induced hormone secreted by skeletal muscle in mice and humans. Irisin promotes brown adipocyte recruitment in white fat and improves systemic metabolism by increasing energy expenditure.

PMID:
22405065
DOI:
10.1016/j.cmet.2012.02.010
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