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Org Lett. 2012 Mar 16;14(6):1576-9. doi: 10.1021/ol300310e. Epub 2012 Mar 8.

Facile syntheses of 3-hydroxyflavones.

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  • 1Chemistry Group Laboratories, TUBITAK UME, Gebze, Kocaeli, Turkey.

Abstract

Modification of the present synthetic methods led to the syntheses of 3-hydroxyflavones in a shorter reaction time, with simple purification and higher yields. Application of the method provided the syntheses of 3HFs having a hydroxyl group on the phenyl ring (ring B) in one step, which is an improvement compared to the four steps, long reaction time, and low yield using the current method available in the literature.

PMID:
22400900
DOI:
10.1021/ol300310e
[PubMed - indexed for MEDLINE]
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