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Caries Res. 2012;46(2):107-12. doi: 10.1159/000336960. Epub 2012 Mar 5.

Colonization of the oral cavity by probiotic bacteria.

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School of Dentistry, Aarhus Faculty of Health Sciences, Aarhus University, Aarhus, Denmark.


The aim of this study was to investigate if three probiotic bacteria present in the milk product Cultura DofilusĀ® naturell could be detected in saliva and on oral mucosal surfaces, and if they colonized dental surfaces in situ in 8 caries-inactive individuals after 8 daily exposures to the milk product for up to 3 days. Bacteria were identified by fluorescence in situ hybridization and confocal laser scanning microscopy. While probiotic bacteria were present sporadically in the oral cavity on mucosal surfaces and in saliva after 3 days of frequent use of the probiotic milk, they were not detected on dental surfaces. Probiotic bacteria may thus contribute to general oral health, but their potential role in biofilm-induced dental diseases remains unclear.

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