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J Crohns Colitis. 2012 Jul;6(6):687-91. doi: 10.1016/j.crohns.2011.12.001. Epub 2012 Jan 17.

Anaemia and iron deficiency in children with inflammatory bowel disease.

Author information

1
NIHR Biomedical Research Unit (Nutrition, Diet & Lifestyle), Southampton General Hospital, SO16 6YD, UK.

Abstract

BACKGROUND AND AIMS:

Anaemia and iron deficiency are common in children with Inflammatory Bowel Disease (IBD) however it is not known if the prevalence of anaemia and iron deficiency alters following diagnosis.

METHODS:

Laboratory results from diagnosis, and at follow up one and two years later were recorded retrospectively in children with IBD recruited from a tertiary centre. Anaemia was defined using WHO standards and iron deficiency defined using published guidelines.

RESULTS:

46 children (16 girls) with Crohn's disease and 34 children (18 girls) with UC were studied. 75% of children with IBD were anaemic at diagnosis, 30% were anaemic at follow up two years later. 90% of children with Crohn's and 95% of children with Ulcerative Colitis (UC) were iron deficient at diagnosis. At follow up two years later 70% of children with Crohn's and 65% of children with UC were iron deficient.

CONCLUSIONS:

Persistent anaemia and iron deficiency are common in childhood IBD, prevalence alters with duration of time from diagnosis.

PMID:
22398100
DOI:
10.1016/j.crohns.2011.12.001
[Indexed for MEDLINE]

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