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Ugeskr Laeger. 2012 Mar 5;174(10):655-6.

[Chronic HBV infection in a two year-old girl in spite of correct HBV vaccination after birth].

[Article in Danish]

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Børneafdeling GGK, Rigshospitalet, Blegdamsvej 9, 2100 København Ø, Denmark.


Our case story is about a two year-old girl who, despite full vaccination with neonatal hepatitis B immunoglobulin and hepatitis B vaccination and revaccination with hepatitis B vaccine at one, two and 12 months of age, got chronic hepatitis B presumably due to intrauterine mother-to-child transmission. Her mother was known to be HBsAg and HBeAg positive with genotype C and a viral load of one billion IU/ml. It is important that children with HBV infection are detected and seen in a special department. Post-vaccination screening of children from HBsAg positive mothers should be considered.

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