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No Shinkei Geka. 2012 Mar;40(3):261-9.

[Case of metastatic malignant melanoma detected by multifocal cerebral hemorrhage].

[Article in Japanese]

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Department of Neurological Surgery, Kagawa University, Kagawa, Japan.


We encountered a case of intracranial metastatic malignant melanoma which caused repeated multiple hemorrhage. Intracranial metastatic malignant melanoma showed high intensity in the magnetic resonance imaging's T1 weighted image, low intensity in T2 weighted image and very low intensity in T2* weighted image. Positron emission tomographic scans are useful for systemic evaluation of active malignancies. The present case underwent tumor removal following re-bleeding. The patient died of repeated hemorrhage one month after the operation. Intracranial metastatic malignant melanoma has a strong propensity to cause intracerebral hemorrhage leading to clinical deterioration. We think that the development of a therapeutic strategy for the treatment of intracranial metastatic malignant melanoma, including its risk management of intracerebral hemorrhage would be great importance.

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