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J Am Acad Dermatol. 2012 Oct;67(4):582-6. doi: 10.1016/j.jaad.2011.11.937. Epub 2012 Mar 2.

The natural history of halo nevi: a retrospective case series.

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1
Northeast Ohio Medical University, Rootstown, Ohio 44483, USA.

Abstract

BACKGROUND:

The time period between onset of depigmentation around the halo nevus (HN) to complete resolution of the nevus and halo has not been well studied.

OBJECTIVE:

We sought to better understand the natural history of the HN.

METHODS:

A retrospective chart review of patients with a clinical diagnosis of HN selected from a private practice database (1994-2010) was performed. In all, 52 patients with 80 HN were identified. The current stage of the HN was determined by a follow-up questionnaire and physical examination of 36 patients with 56 HN.

RESULTS:

Seven HN were excised. Of the remaining 49 HN, 51% (25) demonstrated no change in the halo or nevus after an average of 4.2 years; 14.3% (7) demonstrated partial nevus regression with persistence of the halo after an average of 6.7 years; 4.1% (2) demonstrated complete involution of the nevus with persistent halo depigmentation after an average of 7.7 years; 8.2% (4) demonstrated complete nevus involution with some repigmentation of the halo after an average of 11.8 years; 22.4% (11) demonstrated complete resolution of the nevus with complete repigmentation of the halo after an average of 7.8 years.

LIMITATION:

Some subjects were lost to follow-up. The time of initial HN onset was dependent on patient recall.

CONCLUSION:

These results demonstrate that HN typically persist for a decade or longer. A subgroup may progress through stages of involution with a return to normal-appearing skin, but even these lesions persisted for an average of 7.8 years. Education about the prolonged natural history of HN may reassure patients and avoid unnecessary excision.

PMID:
22387032
DOI:
10.1016/j.jaad.2011.11.937
[Indexed for MEDLINE]
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