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J Am Acad Dermatol. 2012 May;66(5):842.e1-17. doi: 10.1016/j.jaad.2011.01.004. Epub 2012 Mar 2.

Cutis laxa: a review.

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1
Department of Internal Medicine, Division of Dermatology, Washington University School of Medicine and St Louis Children's Hospital, St Louis, Missouri 63110, USA. dberk@dom.wustl.edu

Abstract

Cutis laxa is a rare disorder of elastic tissue resulting in loose, redundant, hypoelastic skin. Both acquired and inherited forms exist, some of which have significant systemic manifestations. Here, we review the various forms of cutis laxa, with focus on the inherited forms. Recent molecular studies have provided many new insights into the causes of cutis laxa and revealed greater genetic heterogeneity than previously appreciated.

PMID:
22387031
DOI:
10.1016/j.jaad.2011.01.004
[Indexed for MEDLINE]
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