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Curr HIV Res. 2012 Apr;10(3):202-10.

The role of bacterial vaginosis and trichomonas in HIV transmission across the female genital tract.

Author information

1
Department of Immunology/Microbiology, Rush University Medical Center, Chicago, IL 60612, USA.

Abstract

Bacterial vaginosis (BV) and Trichomonas vaginalis (TV) infections are both very common and are associated with increased risk of sexual transmission of HIV. There are several mechanisms by which BV and TV could affect susceptibility including inducing pro-inflammatory cytokines and disrupting mucosal barrier function. This review highlights recent advances in our understanding of how these genital conditions lead to an increased risk of HIV infection in women.

PMID:
22384839
PMCID:
PMC3788616
[Indexed for MEDLINE]
Free PMC Article

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