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Ginekol Pol. 2011 Dec;82(12):900-4.

[Antibiotic resistance of Gardnerella vaginalis isolated from cases of bacterial vaginosis].

[Article in Polish]

Author information

1
Katedra Mikrobiologii Collegium Medicum Uniwersytetu Jagiellońskiego w Krakowie, Polska. atomusiak@student.cm-uj.krakow.pl

Abstract

INTRODUCTION:

Gardnerella vaginalis is one of the dominant etiological factors related to bacterial vaginosis. Literature offers a growing number of reports revealing there appear Gardnerella vaginalis strains increasingly resistant to metronidazole.

OBJECTIVES:

The aim of this study was to determine the susceptibility of Gardnerella vaginalis strains isolated from women with bacterial vaginosis to metronidazole, clindamycin and amoxicillin/clavulanic acid.

MATERIAL AND METHODS:

The investigation was performed on collection of 67 Gardnerella vaginalis strains isolated from the group of 604 women participating in the study Antibiotic sensitivity of strains was verified by E-test method (BioMerieux). Interpretation of results was performed in accordance with EUCAST criteria.

RESULTS:

All tested strains, apart from one, were sensitive to clindamycin and amoxicillin/clavulanic acid. The results of susceptibility test to metronidazole indicated that 68.7% (46 out of 67 strains) were resistant to this antibiotic, while all of them were sensitive to both clindamycin and amoxicillin/clavulanic acid.

CONCLUSIONS:

Near future may bring the need to change the treatment regimen of bacterial vaginosis.

PMID:
22384625
[Indexed for MEDLINE]

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