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Pediatr Blood Cancer. 2012 Jul 15;59(1):5-10. doi: 10.1002/pbc.24118. Epub 2012 Feb 29.

Rhabdomyosarcoma: review of the Children's Oncology Group (COG) Soft-Tissue Sarcoma Committee experience and rationale for current COG studies.

Author information

1
Department of Pediatrics, Oregon Health and Science University, Portland, Oregon 97239-3098, USA. malempat@ohsu.edu

Abstract

The prognosis for children and adolescents with rhabdomyosarcoma (RMS) has improved with refinements in multi-modal therapy. Since 1972, the Intergroup Rhabdomyosarcoma Study Group (now the Children's Oncology Group Soft-Tissue Sarcoma Committee) has conducted serial studies for RMS. This review describes the IRSG and COG experience with RMS, presents the current risk stratification definitions, and provides rationale for the current generation of COG RMS studies.

PMID:
22378628
PMCID:
PMC4008325
DOI:
10.1002/pbc.24118
[Indexed for MEDLINE]
Free PMC Article

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